Tagged: genetics

Model of a human brain 0

Single Molecular Event Linked to Mammalian Brain Development

How did humans develop larger brains than our ancestors?  Researchers at the Donnelly Centre for Cellular & Biomolecular research in Toronto have just discovered that mammalian brain development may be linked to a single molecular event that started an evolutionary chain-reaction, leading all the way up to humans. A genetic mutation in protein PTBP1, responsible for neurogenesis (the development of neurons), is said to be the likely precursor to an event set-off by something called ‘alternate splicing’ which occurs when neural proteins are assembled by our DNA. According to these findings, the greater the amount of ‘alternate splicing’ events which occur, the further the development of brain region size...